BNIP3P37

Across TCGA pan-cancer cohorts, BNIP3P37 RNA differs between tumor and matched normal tissue in 8 of 18 cancer types tested, making tumor–normal expression one of BNIP3P37’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where BNIP3P37 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types BNIP3P37 is over-expressed in tumor.

HNSC, BRCA, and LUSC are the cancer types where BNIP3P37 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in BNIP3P37 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	All	II,III,IV	+0.027	.008	7	view →
BRCA	Female	All	+0.126	.016	4	view →
LUSC	All	All	+0.098	.006	4	view →
BLCA	All	All	+0.080	.017	3	view →
LUAD	Male	All	+0.162	.022	2	view →
THCA	Male	III,IV	+0.060	.021	2	view →
LIHC	All	All	+0.021	.031	2	view →
CHOL	All	All	+0.073	.048	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 8 strongest of 8 lineages.

BNIP3P37–HNSC

Open the HNSC breakdown →