BNIP3P31

Across TCGA pan-cancer cohorts, BNIP3P31 RNA is linked to patient survival in 10 of 34 cancer types, making it the most broadly survival-associated BNIP3P31 data layer.

The strongest signal is observed in ovarian serous cystadenocarcinoma (OV), where higher BNIP3P31 RNA is associated with better overall survival. In most high-consensus cancer types, elevated BNIP3P31 expression acts as an unfavorable survival marker, although some lineages such as OV and HNSC show a favorable association.

OV, UCEC, and HNSC are the cancer types where BNIP3P31 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
OV	OS	Tertile	IV	0.735	0.558	.011	64	view →
UCEC	OS	Tertile	All	0.872	0.936	.003	60	view →
HNSC	DFS	Tertile	All	0.624	0.284	.002	51	view →
BLCA	DFS	Tertile	III,IV	0.166	0.498	.010	27	view →
PCPG	OS	Tertile	All	0.571	0.963	<.001	27	view →
LGG	DFS	Tertile	All	0.576	0.358	.003	27	view →
ESCA	OS	Tertile	III,IV	0.720	0.366	.025	18	view →
UCS	OS	Tertile	IV	0.269	0.624	.042	18	view →
KIRP	OS	Tertile	All	0.712	0.911	.045	6	view →
SKCM	OS	Tertile	All	0.928	0.764	.046	3	view →

Pink = unfavorable, green = favorable. Showing the 10 strongest of 10 lineages.

BNIP3P31–OV (OS)

Open the OV breakdown →