BNIP3P15

Across TCGA pan-cancer cohorts, BNIP3P15 RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated BNIP3P15 data layer.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where higher BNIP3P15 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated BNIP3P15 expression acts as an unfavorable survival marker, although some lineages such as UVM and LUAD show a favorable association.

LIHC, LGG, and UCEC are the cancer types where BNIP3P15 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LIHC	OS	Tertile	III,IV	0.121	0.580	<.001	45	view →
LGG	DFS	Median	All	0.670	0.808	<.001	44	view →
UCEC	DFS	Quartile	II,III,IV	0.737	0.846	.007	28	view →
UVM	OS	Tertile	All	1.000	0.516	.026	24	view →
READ	OS	Tertile	III,IV	0.403	0.741	.006	18	view →
LUSC	OS	Tertile	IV	0.001	0.651	.025	18	view →
LUAD	OS	Quartile	All	0.655	0.203	.002	16	view →
PAAD	DFS	Tertile	All	0.144	0.314	.039	12	view →
COAD	DFS	Tertile	III,IV	0.483	0.727	.025	12	view →
THCA	OS	Median	All	0.985	0.901	.019	10	view →
KICH	DFS	Tertile	III,IV	0.043	0.897	.045	9	view →
STAD	DFS	Tertile	IV	0.083	0.379	.001	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

BNIP3P15–LIHC (OS)

Open the LIHC breakdown →