BNIP3P15

Across TCGA pan-cancer cohorts, BNIP3P15 RNA differs between tumor and matched normal tissue in 11 of 18 cancer types tested, making tumor–normal expression one of BNIP3P15’s most consistent transcriptional readouts.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where BNIP3P15 RNA is repressed in tumor relative to normal tissue. In most cancer types BNIP3P15 is over-expressed in tumor, although a few such as LUSC and COAD show the opposite, repressed pattern.

LUSC, KIRC, and COAD are the cancer types where BNIP3P15 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in BNIP3P15 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUSC	Male	All	−0.455	<.001	7	view →
KIRC	Male	II,III,IV	+0.409	<.001	6	view →
COAD	Male	All	−0.285	<.001	5	view →
KICH	All	All	−0.265	<.001	5	view →
HNSC	Female	III,IV	−0.098	.025	3	view →
BLCA	Female	IV	+1.610	.028	2	view →
PAAD	Female	All	−0.725	.005	2	view →
THCA	All	All	+0.428	.041	2	view →
PRAD	All	All	−0.364	<.001	2	view →
LUAD	All	II,III,IV	−0.395	.035	1	view →
READ	All	II,III,IV	−0.335	.034	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 11 strongest of 11 lineages.

BNIP3P15–LUSC

Open the LUSC breakdown →