BNC2

Across TCGA cell cohorts, BNC2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,948 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible BNC2-associated GO terms across cancer lineages are Actin filament depolymerization, Positive regulation of cell-substrate junction organization, and PML body organization. Each is linked with BNC2 in more than 11 cancer types. Because this analysis shows association rather than direction, both BNC2-to-partner and partner-to-BNC2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Actin filament depolymerization grouped by BNC2-low versus BNC2-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (BNC2→partner) and Y-score (partner→BNC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Actin filament depolymerization →	+0.223	+1.580	<.001	<.001	3	12
BONE	Positive regulation of cell-substrate junction organization →	+0.179	+1.836	<.001	<.001	3	11
LUNG_NSCLC_LUSC	PML body organization →	+0.240	+1.835	<.001	<.001	3	11
LUNG_NSCLC_LUSC	Establishment of epithelial cell apical/basal polarity →	+0.215	+1.548	<.001	<.001	3	11
BREAST	Protein depolymerization →	+0.132	+1.701	<.001	<.001	3	11
BONE	Regulation of cell-substrate junction organization →	+0.194	+2.247	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,948 associations by consensus.

Actin filament depolymerization by BNC2 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →