BNC2-AS1

Across TCGA pan-cancer cohorts, BNC2-AS1 RNA differs between tumor and matched normal tissue in 13 of 18 cancer types tested, making tumor–normal expression one of BNC2-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where BNC2-AS1 RNA is repressed in tumor relative to normal tissue. In most cancer types BNC2-AS1 is over-expressed in tumor, although a few such as KICH and STAD show the opposite, repressed pattern.

KICH, STAD, and COAD are the cancer types where BNC2-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in BNC2-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KICH	Female	II,III,IV	−2.820	<.001	11	view →
STAD	All	All	−0.786	<.001	9	view →
COAD	All	II,III,IV	−0.585	<.001	9	view →
BLCA	Male	All	−1.259	<.001	8	view →
LUAD	All	III,IV	−0.801	<.001	8	view →
UCEC	All	II,III,IV	−2.902	<.001	6	view →
BRCA	All	II,III,IV	−0.573	<.001	6	view →
LUSC	Male	All	−0.423	.001	6	view →
HNSC	Male	All	−0.410	.001	4	view →
THCA	Female	All	−1.081	<.001	3	view →
READ	Female	All	−1.294	.007	2	view →
PRAD	All	All	−0.305	.036	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 13 lineages.

BNC2-AS1–KICH

Open the KICH breakdown →