BNC1

Across TCGA patient cohorts, BNC1 protein abundance is significantly associated with the RNA expression of many other genes, with 1,836 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible BNC1-associated genes across cancer lineages are TUBA1C, AKAP5, and KRT14. Each is linked with BNC1 in more than 1 cancer types. Because this analysis shows association rather than direction, both BNC1-to-partner and partner-to-BNC1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, BNC1 versus TUBA1C in LSCC, with a Pearson correlation of 0.51.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BNC1→partner) and Y-score (partner→BNC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	TUBA1C →	+0.777	+0.807	<.001	.003	3	2
LSCC	AKAP5 →	-0.459	-0.486	<.001	.007	3	2
LSCC	KRT14 →	+4.971	+0.762	<.001	.002	3	2
LSCC	GJB3 →	+1.088	+0.694	<.001	<.001	3	2
LSCC	GJB5 →	+1.963	+0.829	.002	<.001	3	2
LSCC	S100A2 →	+3.263	+1.109	.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,836 associations by consensus.

BNC1 vs TUBA1C — LSCC

Explore this scatter interactively →