BNC1

Across TCGA cell cohorts, BNC1 mutation is significantly associated with the RNA expression of many other genes, with 1,496 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible BNC1-associated genes across cancer lineages are LGALS13, TAAR8, and OR56A4. Each is linked with BNC1 in more than 1 cancer types. Because this analysis shows association rather than direction, both BNC1-to-partner and partner-to-BNC1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LGALS13 grouped by BNC1-low versus BNC1-high in PANCREAS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BNC1→partner) and Y-score (partner→BNC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	LGALS13 →	+0.045	+4.614	<.001	.004	3	1
PANCREAS	TAAR8 →	+0.017	+4.614	<.001	.004	3	1
PANCREAS	OR56A4 →	+0.010	+4.614	<.001	.004	3	1
PANCREAS	KRTAP5-5 →	+0.033	+4.237	<.001	.006	3	1
PANCREAS	OR13C5 →	+0.010	+4.614	<.001	.004	3	1
SOFT_TISSUE	CST9L →	+0.021	+4.369	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,496 associations by consensus.

LGALS13 by BNC1 expression — PANCREAS

Explore this box plot interactively →