BMPR1B

Across TCGA cell cohorts, BMPR1B RNA expression is significantly associated with the go_rna of many other GO terms, with 1,892 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible BMPR1B-associated GO terms across cancer lineages are Chromosomal 5-methylcytosine DNA demethylation pathway, Regulation of ferroptosis, and Acetylcholine catabolic process. Each is linked with BMPR1B in more than 5 cancer types. Because this analysis shows association rather than direction, both BMPR1B-to-partner and partner-to-BMPR1B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Chromosomal 5-methylcytosine DNA demethylation pathway grouped by BMPR1B-low versus BMPR1B-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (BMPR1B→partner) and Y-score (partner→BMPR1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Chromosomal 5-methylcytosine DNA demethylation pathway →	+0.153	+1.127	<.001	<.001	3	6
BLOOD_Lymphoma	Regulation of ferroptosis →	+0.107	+0.583	.001	.007	3	6
SOFT_TISSUE	Acetylcholine catabolic process →	+0.834	+0.887	.001	.001	3	5
OVARY	Regulation of skeletal muscle contraction by calcium ion signaling →	-0.109	-1.272	.005	.001	3	5
URINARY_TRACT	Positive regulation of synaptic vesicle endocytosis →	-0.135	-0.693	<.001	<.001	3	5
URINARY_TRACT	Positive regulation of synaptic vesicle recycling →	-0.105	-0.658	.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,892 associations by consensus.

Chromosomal 5-methylcytosine DNA demethylation pathway by BMPR1B expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →