BMPR1B

Across TCGA cell cohorts, BMPR1B mutation is significantly associated with the mutation status of many other genes, with 2,958 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible BMPR1B-associated genes across cancer lineages are SYNJ2, SHROOM3, and OR2G2. Each is linked with BMPR1B in more than 3 cancer types. Because this analysis shows association rather than direction, both BMPR1B-to-partner and partner-to-BMPR1B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SYNJ2 grouped by BMPR1B-low versus BMPR1B-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BMPR1B→partner) and Y-score (partner→BMPR1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	SYNJ2 →	+3.316	+3.906	.004	.004	1	4
SKIN	SHROOM3 →	+3.053	+3.718	.006	.006	1	4
LUNG_NSCLC_LUAD	OR2G2 →	+4.187	+5.000	.008	.008	1	4
PANCREAS	ACOT7 →	+5.115	+5.115	.005	.005	1	3
BLOOD_Lymphoma	NIN →	+3.584	+4.922	.001	.001	1	3
BLOOD_Lymphoma	COL11A1 →	+3.362	+4.754	.002	.002	1	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,958 associations by consensus.

SYNJ2 by BMPR1B expression — SKIN

Explore this box plot interactively →