BMPR1B-DT

Across TCGA pan-cancer cohorts, BMPR1B-DT RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated BMPR1B-DT data layer.

The strongest signal is observed in rectum adenocarcinoma (READ), where higher BMPR1B-DT RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated BMPR1B-DT expression acts as an unfavorable survival marker, although some lineages such as OV and UCEC show a favorable association.

READ, OV, and MESO are the cancer types where BMPR1B-DT RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
READ	DFS	Tertile	II,III,IV	0.415	0.698	.001	99	view →
OV	OS	Median	All	0.747	0.629	<.001	58	view →
MESO	OS	Tertile	All	0.257	0.445	.002	53	view →
KIRC	OS	Quartile	II,III,IV	0.674	0.842	.005	47	view →
UCEC	DFS	Median	All	0.719	0.566	<.001	46	view →
UVM	DFS	Tertile	All	0.226	0.858	<.001	45	view →
ACC	DFS	Tertile	III,IV	0.089	0.432	.008	18	view →
HNSC	DFS	Tertile	IV	0.189	0.442	.009	15	view →
CHOL	DFS	Tertile	All	0.126	0.573	.044	9	view →
BLCA	OS	Tertile	IV	0.266	0.601	.029	9	view →
THCA	DFS	Tertile	IV	0.027	0.937	<.001	9	view →
LUAD	DFS	Median	II,III,IV	0.343	0.607	.024	8	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

BMPR1B-DT–READ (DFS)

Open the READ breakdown →