BMPR1A

Across TCGA patient cohorts, BMPR1A protein abundance is significantly associated with the RNA expression of many other genes, with 1,880 significant associations in total. GBM shows the largest number of these associations.

The most reproducible BMPR1A-associated genes across cancer lineages are GABRR2, RASGRP3, and PLPP3. Each is linked with BMPR1A in more than 1 cancer types. Because this analysis shows association rather than direction, both BMPR1A-to-partner and partner-to-BMPR1A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, BMPR1A versus GABRR2 in LSCC, with a Pearson correlation of -0.81.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BMPR1A→partner) and Y-score (partner→BMPR1A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	GABRR2 →	-1.022	-0.471	<.001	.001	3	2
LSCC	RASGRP3 →	-0.803	-0.633	<.001	.005	3	2
LUAD	PLPP3 →	+0.964	+0.402	<.001	.001	3	2
GBM	SLC6A1-AS1 →	+0.931	+0.482	.005	<.001	3	2
LSCC	GLIS3-AS1 →	+0.901	+0.471	.003	.001	3	2
OV	SGSM3 →	-0.165	-0.312	.006	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,880 associations by consensus.

BMPR1A vs GABRR2 — LSCC

Explore this scatter interactively →