BMPR1A

Across TCGA patient cohorts, BMPR1A mutation is significantly associated with the RNA expression of many other genes, with 2,577 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible BMPR1A-associated genes across cancer lineages are RNU6-932P, MIR375, and MIR5787. Each is linked with BMPR1A in more than 1 cancer types. Because this analysis shows association rather than direction, both BMPR1A-to-partner and partner-to-BMPR1A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-932P grouped by BMPR1A-low versus BMPR1A-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BMPR1A→partner) and Y-score (partner→BMPR1A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	RNU6-932P →	+0.548	+5.306	<.001	.006	3	2
LUAD	MIR375 →	+0.669	+3.999	<.001	.005	3	2
SKCM	MIR5787 →	+0.474	+4.513	<.001	.009	3	2
UCEC	RNA5SP419 →	+0.569	+1.907	<.001	.003	3	2
UCEC	YTHDF3-AS1 →	+0.498	+1.790	.002	.004	3	1
UCEC	RPS10-NUDT3 →	+0.223	+2.070	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,577 associations by consensus.

RNU6-932P by BMPR1A expression — CESC

Explore this box plot interactively →