BMPR1A

Across TCGA cell cohorts, BMPR1A RNA expression is significantly associated with the go_rna of many other GO terms, with 3,935 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible BMPR1A-associated GO terms across cancer lineages are Cardiac septum cell differentiation, Atrioventricular node cell differentiation, and Atrioventricular node cell development. Each is linked with BMPR1A in more than 15 cancer types. Because this analysis shows association rather than direction, both BMPR1A-to-partner and partner-to-BMPR1A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cardiac septum cell differentiation grouped by BMPR1A-low versus BMPR1A-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (BMPR1A→partner) and Y-score (partner→BMPR1A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Cardiac septum cell differentiation →	+0.169	+1.016	<.001	<.001	3	16
LUNG_NSCLC_LUSC	Atrioventricular node cell differentiation →	+0.169	+1.016	<.001	<.001	3	16
LUNG_NSCLC_LUSC	Atrioventricular node cell development →	+0.169	+1.016	<.001	<.001	3	16
STOMACH	Negative regulation of smoothened signaling pathway →	+0.074	+1.165	.002	.001	3	14
PANCREAS	Regulation of sister chromatid cohesion →	+0.122	+1.095	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	DNA strand elongation →	+0.190	+1.285	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,935 associations by consensus.

Cardiac septum cell differentiation by BMPR1A expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →