Across TCGA cell cohorts, BMP8A RNA expression is significantly associated with the go_rna of many other GO terms, with 2,871 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible BMP8A-associated GO terms across cancer lineages are Negative regulation of mRNA splicing, via spliceosome, Negative regulation of mRNA processing, and Positive regulation of intracellular steroid hormone receptor signaling pathway. Each is linked with BMP8A in more than 11 cancer types. Because this analysis shows association rather than direction, both BMP8A-to-partner and partner-to-BMP8A results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (BMP8A→partner) and Y-score (partner→BMP8A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Negative regulation of mRNA splicing, via spliceosome →	+0.142	+0.408	.001	.002	3	12
STOMACH	Negative regulation of mRNA processing →	+0.144	+0.446	<.001	<.001	3	12
UPPER_AERODIGESTIVE_TRACT	Positive regulation of intracellular steroid hormone receptor signaling pathway →	+0.153	+0.203	<.001	.001	3	11
OESOPHAGUS	Negative regulation of syncytium formation by plasma membrane fusion →	+0.150	+0.308	<.001	.005	3	11
STOMACH	Regulation of RNA splicing →	+0.104	+0.438	<.001	<.001	3	11
UPPER_AERODIGESTIVE_TRACT	Transcription pausing by RNA polymerase II →	+0.130	+0.199	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,871 associations by consensus.

Exploration

BMP8A survival (RNA) · tumor vs normal (RNA) · all BMP8A data types