Across TCGA cell cohorts, BMP8A mutation is significantly associated with the RNA expression of many other genes, with 6 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible BMP8A-associated genes across cancer lineages are FABP12, SYNPR, and TPD52L3. Each is linked with BMP8A in more than 1 cancer types. Because this analysis shows association rather than direction, both BMP8A-to-partner and partner-to-BMP8A results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BMP8A→partner) and Y-score (partner→BMP8A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	FABP12 →	+0.116	+4.981	.002	.008	3	1
BLOOD_Leukemia	SYNPR →	+0.034	+4.409	.002	.005	3	1
BLOOD_Leukemia	TPD52L3 →	+0.009	+4.539	<.001	.007	3	1
BLOOD_Leukemia	FAM9A →	+0.014	+4.539	<.001	.007	3	1
BLOOD_Leukemia	IZUMO3 →	+0.054	+4.969	<.001	.003	3	1
BLOOD_Leukemia	SLURP2 →	+0.056	+5.060	.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

Exploration

BMP8A survival (RNA) · tumor vs normal (RNA) · all BMP8A data types