BMP7-AS1

Across TCGA pan-cancer cohorts, BMP7-AS1 RNA is linked to patient survival in 12 of 34 cancer types, making it the most broadly survival-associated BMP7-AS1 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher BMP7-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated BMP7-AS1 expression acts as an unfavorable survival marker, although some lineages such as OV and KIRP show a favorable association.

KIRC, ACC, and THCA are the cancer types where BMP7-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Tertile	IV	0.098	0.650	<.001	84	view →
ACC	OS	Tertile	All	0.273	0.802	.017	45	view →
THCA	OS	Tertile	III,IV	0.859	0.986	.008	22	view →
OV	OS	Tertile	IV	0.786	0.465	.006	20	view →
TGCT	DFS	Tertile	II,III,IV	0.088	0.917	.010	18	view →
UCEC	OS	Tertile	All	0.337	0.708	.011	18	view →
KIRP	DFS	Tertile	III,IV	0.865	0.608	.014	17	view →
LGG	DFS	Tertile	All	0.275	0.436	.013	15	view →
HNSC	OS	Tertile	All	0.496	0.373	.027	9	view →
LUSC	OS	Tertile	III,IV	0.726	0.460	.031	6	view →
COAD	DFS	Median	II,III,IV	0.655	0.791	.009	5	view →
READ	DFS	Quartile	IV	0.346	0.669	.028	3	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 12 lineages.

BMP7-AS1–KIRC (DFS)

Open the KIRC breakdown →