BMP7-AS1

Across TCGA pan-cancer cohorts, BMP7-AS1 RNA differs between tumor and matched normal tissue in 7 of 18 cancer types tested, making tumor–normal expression one of BMP7-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where BMP7-AS1 RNA is repressed in tumor relative to normal tissue. In most cancer types BMP7-AS1 is over-expressed in tumor, although a few such as THCA and KIRC show the opposite, repressed pattern.

THCA, COAD, and UCEC are the cancer types where BMP7-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in BMP7-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	All	II,III,IV	−0.119	.002	4	view →
COAD	All	All	+0.118	.001	4	view →
UCEC	All	All	+0.069	.039	2	view →
LUSC	All	All	+0.032	.005	2	view →
KIRP	All	All	+0.055	.041	1	view →
HNSC	All	All	+0.033	.032	1	view →
KIRC	Male	III,IV	−0.028	.049	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 7 strongest of 7 lineages.

BMP7-AS1–THCA

Open the THCA breakdown →