BMP6

Across TCGA cell cohorts, BMP6 mutation is significantly associated with the RNA expression of many other genes, with 29 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible BMP6-associated genes across cancer lineages are ELOA3DP, OR6Q1, and KCNA1. Each is linked with BMP6 in more than 2 cancer types. Because this analysis shows association rather than direction, both BMP6-to-partner and partner-to-BMP6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ELOA3DP grouped by BMP6-low versus BMP6-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BMP6→partner) and Y-score (partner→BMP6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	ELOA3DP →	+0.088	+3.142	<.001	.004	3	3
LARGE_INTESTINE	OR6Q1 →	+0.012	+3.700	<.001	.009	3	2
SOFT_TISSUE	KCNA1 →	+0.321	+4.176	.006	.001	3	1
SOFT_TISSUE	PROK2 →	+0.645	+3.607	.003	.006	3	1
SOFT_TISSUE	VN1R2 →	+0.050	+3.584	<.001	.004	3	1
LUNG_NSCLC_LUAD	ECRG4 →	+0.050	+3.188	.002	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 29 associations by consensus.

ELOA3DP by BMP6 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →