BMP3

Across TCGA patient cohorts, BMP3 mutation is significantly associated with the RNA expression of many other genes, with 4,961 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible BMP3-associated genes across cancer lineages are RN7SL478P, RNA5SP153, and RN7SKP46. Each is linked with BMP3 in more than 1 cancer types. Because this analysis shows association rather than direction, both BMP3-to-partner and partner-to-BMP3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL478P grouped by BMP3-low versus BMP3-high in READ.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BMP3→partner) and Y-score (partner→BMP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
READ	RN7SL478P →	+0.267	+5.219	<.001	.006	3	2
BRCA	RNA5SP153 →	+0.232	+8.057	<.001	.005	3	2
LUSC	RN7SKP46 →	+0.105	+4.438	.009	.006	3	2
LUSC	RNU6-467P →	+0.275	+4.906	<.001	.003	3	2
LUAD	RNU6-937P →	+0.518	+3.835	.003	.003	3	2
LUAD	ARPC1BP1 →	+0.293	+3.520	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,961 associations by consensus.

RN7SL478P by BMP3 expression — READ

Explore this box plot interactively →