BMP3

Across TCGA cell cohorts, BMP3 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible BMP3-associated genes across cancer lineages are TSPY8 and MUC21. Each is linked with BMP3 in more than 1 cancer types. Because this analysis shows association rather than direction, both BMP3-to-partner and partner-to-BMP3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TSPY8 grouped by BMP3-low versus BMP3-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BMP3→partner) and Y-score (partner→BMP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	TSPY8 →	+0.300	+4.347	<.001	.001	3	1
SKIN	MUC21 →	+0.035	+3.523	<.001	.008	1	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

TSPY8 by BMP3 expression — SKIN

Explore this box plot interactively →