BMP10

Across TCGA pan-cancer cohorts, BMP10 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of BMP10’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where BMP10 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types BMP10 is over-expressed in tumor, although a few such as LIHC and CHOL show the opposite, repressed pattern.

KIRC, LIHC, and CHOL are the cancer types where BMP10 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in BMP10 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	All	All	+0.020	<.001	11	view →
LIHC	Male	All	−1.212	<.001	8	view →
CHOL	All	All	−1.026	<.001	5	view →
HNSC	Female	IV	+0.058	.002	4	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

BMP10–KIRC

Open the KIRC breakdown →