BMP1

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, BMP1 protein abundance is significantly associated with the RNA expression of many other genes, with 16,107 significant associations in total. GBM shows the largest number of these associations.

The most reproducible BMP1-associated genes across cancer lineages are MXRA5, SERPINE1, and P3H1. Each is linked with BMP1 in more than 8 cancer types. Because this analysis shows association rather than direction, both BMP1-to-partner and partner-to-BMP1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, BMP1 versus MXRA5 in CCRCC, with a Pearson correlation of 0.75.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BMP1→partner) and Y-score (partner→BMP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
CCRCCMXRA5 →+2.196+1.369<.001.00139
COADSERPINE1 →+2.456+1.029<.001<.00139
OVP3H1 →+1.216+1.107<.001<.00139
COADSERPINH1 →+1.347+1.143<.001<.00139
OVCOL1A1 →+2.557+0.815<.001<.00138
LUADCOL12A1 →+1.471+0.558<.001<.00138
Each partner links to its Q-omics profile. Showing the 6 strongest of 16,107 associations by consensus.

BMP1 vs MXRA5 — CCRCC

Per-sample scatter of BMP1 vs MXRA5 in CCRCC (Pearson r = 0.75).

Explore this scatter interactively →

Exploration