BMP1

Across TCGA patient cohorts, BMP1 mutation is significantly associated with the RNA expression of many other genes, with 4,303 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible BMP1-associated genes across cancer lineages are RFKP1, OXSM, and BUB3. Each is linked with BMP1 in more than 3 cancer types. Because this analysis shows association rather than direction, both BMP1-to-partner and partner-to-BMP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RFKP1 grouped by BMP1-low versus BMP1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BMP1→partner) and Y-score (partner→BMP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RFKP1 →	+0.056	+2.032	.002	<.001	3	4
SKCM	OXSM →	+0.390	+1.879	<.001	.004	3	3
UCEC	BUB3 →	+0.342	+2.075	<.001	<.001	3	3
UCEC	IGFBP7 →	-0.479	-1.967	.002	<.001	3	3
COAD	FAXDC2 →	-0.759	-2.687	.002	.006	3	3
UCEC	RAD51 →	+0.529	+1.818	<.001	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,303 associations by consensus.

RFKP1 by BMP1 expression — UCEC

Explore this box plot interactively →