BMP1

Across TCGA cell cohorts, BMP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,156 significant associations in total. BONE shows the largest number of these associations.

The most reproducible BMP1-associated GO terms across cancer lineages are Regulation of cell-matrix adhesion, Regulation of proteolysis, and Cell-substrate adhesion. Each is linked with BMP1 in more than 16 cancer types. Because this analysis shows association rather than direction, both BMP1-to-partner and partner-to-BMP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of cell-matrix adhesion grouped by BMP1-low versus BMP1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (BMP1→partner) and Y-score (partner→BMP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Regulation of cell-matrix adhesion →	+0.123	+1.282	<.001	<.001	3	17
BONE	Regulation of proteolysis →	+0.155	+2.266	<.001	<.001	3	17
BONE	Cell-substrate adhesion →	+0.201	+2.123	<.001	<.001	3	17
BONE	Gliogenesis →	+0.119	+1.983	<.001	<.001	3	17
BONE	Regulation of cell-substrate adhesion →	+0.115	+1.410	<.001	<.001	3	17
LIVER	Substrate adhesion-dependent cell spreading →	+0.176	+2.261	.003	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,156 associations by consensus.

Regulation of cell-matrix adhesion by BMP1 expression — BONE

Explore this box plot interactively →