BMI1

Across TCGA cell cohorts, BMI1 RNA expression is significantly associated with the RNA expression of many other genes, with 9,637 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible BMI1-associated genes across cancer lineages are COMMD3, KIF5B, and YME1L1. Each is linked with BMI1 in more than 19 cancer types. Because this analysis shows association rather than direction, both BMI1-to-partner and partner-to-BMI1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, BMI1 versus COMMD3 in BLOOD_Myeloma, with a Pearson correlation of 0.91.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BMI1→partner) and Y-score (partner→BMI1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	COMMD3 →	+1.803	+2.024	<.001	<.001	3	20
OESOPHAGUS	KIF5B →	+1.099	+0.908	<.001	<.001	3	15
OESOPHAGUS	YME1L1 →	+0.939	+1.026	<.001	<.001	3	15
STOMACH	CUL2 →	+1.169	+1.291	<.001	<.001	3	15
UPPER_AERODIGESTIVE_TRACT	WAC →	+0.914	+0.888	<.001	<.001	3	15
LUNG_SCLC	ABI1 →	+0.887	+1.409	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,637 associations by consensus.

BMI1 vs COMMD3 — BLOOD_Myeloma

Explore this scatter interactively →