BMI1

Across TCGA cell cohorts, BMI1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,650 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible BMI1-associated GO terms across cancer lineages are Positive regulation of immature T cell proliferation, Positive regulation of immature T cell proliferation in thymus, and Positive regulation of ubiquitin-protein transferase activity. Each is linked with BMI1 in more than 13 cancer types. Because this analysis shows association rather than direction, both BMI1-to-partner and partner-to-BMI1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of immature T cell proliferation grouped by BMI1-low versus BMI1-high in KIDNEY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (BMI1→partner) and Y-score (partner→BMI1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	Positive regulation of immature T cell proliferation →	+0.775	+1.024	.004	.001	3	14
KIDNEY	Positive regulation of immature T cell proliferation in thymus →	+0.775	+1.024	.004	.001	3	14
LUNG_SCLC	Positive regulation of ubiquitin-protein transferase activity →	+0.118	+0.871	.001	.001	3	13
SOFT_TISSUE	Regulation of ubiquitin-protein transferase activity →	+0.098	+1.011	<.001	<.001	3	12
LARGE_INTESTINE	Mitotic spindle assembly →	+0.080	+0.908	.001	<.001	3	11
STOMACH	DNA synthesis involved in DNA repair →	+0.085	+0.912	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,650 associations by consensus.

Positive regulation of immature T cell proliferation by BMI1 expression — KIDNEY

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