BMERB1

Across TCGA patient cohorts, BMERB1 protein abundance is significantly associated with the RNA expression of many other genes, with 5,411 significant associations in total. GBM shows the largest number of these associations.

The most reproducible BMERB1-associated genes across cancer lineages are NDNF, OSBPL3, and GALNT16. Each is linked with BMERB1 in more than 1 cancer types. Because this analysis shows association rather than direction, both BMERB1-to-partner and partner-to-BMERB1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, BMERB1 versus NDNF in PDAC, with a Pearson correlation of -0.47.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BMERB1→partner) and Y-score (partner→BMERB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	NDNF →	-1.367	-1.078	<.001	<.001	3	2
GBM	OSBPL3 →	-0.680	-0.544	<.001	.001	3	2
BRCA	GALNT16 →	+1.106	+0.556	.002	.004	3	2
BRCA	PRPH2 →	+0.824	+0.704	.001	.001	3	2
BRCA	TCEAL4 →	+0.733	+0.487	<.001	.001	3	2
BRCA	LARGE1 →	+0.935	+0.765	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,411 associations by consensus.

BMERB1 vs NDNF — PDAC

Explore this scatter interactively →