BLZF1

Across TCGA pan-cancer cohorts, BLZF1 RNA is linked to patient survival in 27 of 34 cancer types, making it the most broadly survival-associated BLZF1 data layer compared with 5 for mutation status and 5 for mass-spec protein.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where higher BLZF1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated BLZF1 expression acts as an unfavorable survival marker, although some lineages such as KIRC and COAD show a favorable association.

KIRP, KIRC, and ACC are the cancer types where BLZF1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRP	DFS	Tertile	All	0.841	0.966	<.001	100	view →
KIRC	DFS	Tertile	All	0.721	0.524	<.001	90	view →
ACC	DFS	Median	All	0.163	0.694	<.001	86	view →
LGG	DFS	Median	All	0.772	0.889	<.001	46	view →
LIHC	OS	Tertile	All	0.704	0.865	<.001	45	view →
LUAD	OS	Quartile	All	0.753	0.922	.001	43	view →
UVM	DFS	Quartile	III,IV	0.170	0.814	.002	31	view →
PAAD	OS	Median	All	0.280	0.532	.004	30	view →
KICH	DFS	Quartile	II,III,IV	0.433	0.928	.004	27	view →
STAD	DFS	Quartile	II,III,IV	0.591	0.837	.022	21	view →
SCLC	DFS	Median	IV	0.137	0.559	.008	18	view →
UCEC	DFS	Quartile	All	0.623	0.802	.015	10	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 27 lineages.

BLZF1–KIRP (DFS)

Open the KIRP breakdown →