Across TCGA patient cohorts, BLOC1S5 protein abundance is significantly associated with the RNA expression of many other genes, with 8,293 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible BLOC1S5-associated genes across cancer lineages are DENND2D, IRAK4, and PGPEP1. Each is linked with BLOC1S5 in more than 3 cancer types. Because this analysis shows association rather than direction, both BLOC1S5-to-partner and partner-to-BLOC1S5 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BLOC1S5→partner) and Y-score (partner→BLOC1S5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	DENND2D →	+0.664	+0.220	.002	<.001	3	4
UCEC	IRAK4 →	+0.467	+0.312	<.001	<.001	3	4
HNSC	PGPEP1 →	+0.774	+0.291	<.001	.006	3	4
BRCA	ATP2A3 →	+1.208	+0.259	<.001	<.001	3	4
OV	SERPINB1 →	+0.645	+0.358	<.001	<.001	3	3
COAD	ZNF182 →	+0.558	+1.278	.004	.003	2	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,293 associations by consensus.

Exploration

BLOC1S5 survival (RNA) · tumor vs normal (RNA) · all BLOC1S5 data types