Across TCGA patient cohorts, BLOC1S3 protein abundance is significantly associated with the RNA expression of many other genes, with 7,330 significant associations in total. GBM shows the largest number of these associations.

The most reproducible BLOC1S3-associated genes across cancer lineages are F13A1, ABCA8, and DLG2. Each is linked with BLOC1S3 in more than 3 cancer types. Because this analysis shows association rather than direction, both BLOC1S3-to-partner and partner-to-BLOC1S3 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BLOC1S3→partner) and Y-score (partner→BLOC1S3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	F13A1 →	+1.533	+0.208	<.001	<.001	3	3
HNSC	ABCA8 →	+0.831	+0.246	<.001	<.001	3	3
HNSC	DLG2 →	+0.622	+0.255	<.001	<.001	3	3
HNSC	MEOX2 →	+0.789	+0.191	.003	.008	3	3
HNSC	MAN1C1 →	+0.837	+0.261	<.001	<.001	3	3
GBM	DAB2 →	+0.860	+0.264	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,330 associations by consensus.

Exploration

BLOC1S3 survival (RNA) · tumor vs normal (RNA) · all BLOC1S3 data types