BLOC1S1

Across TCGA patient cohorts, BLOC1S1 protein abundance is significantly associated with the RNA expression of many other genes, with 9,041 significant associations in total. GBM shows the largest number of these associations.

The most reproducible BLOC1S1-associated genes across cancer lineages are FGF14, CCNA2, and LINC02718. Each is linked with BLOC1S1 in more than 3 cancer types. Because this analysis shows association rather than direction, both BLOC1S1-to-partner and partner-to-BLOC1S1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, BLOC1S1 versus FGF14 in HNSC, with a Pearson correlation of 0.32.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BLOC1S1→partner) and Y-score (partner→BLOC1S1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	FGF14 →	+0.613	+0.216	<.001	.001	3	4
HNSC	CCNA2 →	-0.741	-0.216	<.001	<.001	3	4
GBM	LINC02718 →	+0.579	+0.172	<.001	.002	3	4
HNSC	H2BC17 →	-1.364	-0.248	.001	<.001	3	4
HNSC	H2AC16 →	-1.461	-0.226	<.001	.001	3	4
HNSC	SMIM33 →	+0.312	+0.158	.004	.003	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,041 associations by consensus.

BLOC1S1 vs FGF14 — HNSC

Explore this scatter interactively →