BLK

Across TCGA patient cohorts, BLK protein abundance is significantly associated with the RNA expression of many other genes, with 2,337 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible BLK-associated genes across cancer lineages are PLTP, BCKDK, and RASAL3. Each is linked with BLK in more than 1 cancer types. Because this analysis shows association rather than direction, both BLK-to-partner and partner-to-BLK results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, BLK versus PLTP in HNSC, with a Pearson correlation of 0.75.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BLK→partner) and Y-score (partner→BLK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	PLTP →	+1.894	+1.004	.002	.008	3	1
HNSC	BCKDK →	+0.700	+1.003	.004	.008	3	1
HNSC	RASAL3 →	+1.182	+1.004	.006	.008	3	1
HNSC	VSIR →	+1.343	+1.004	<.001	.008	3	1
HNSC	FBXW7 →	+0.632	+1.003	.004	.008	3	1
HNSC	CCR6 →	+0.239	+1.003	.003	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,337 associations by consensus.

BLK vs PLTP — HNSC

Explore this scatter interactively →