BIRC6-AS2

Across TCGA pan-cancer cohorts, BIRC6-AS2 RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated BIRC6-AS2 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher BIRC6-AS2 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated BIRC6-AS2 expression acts as an unfavorable survival marker, although some lineages such as BLCA and COAD show a favorable association.

KIRC, ACC, and KICH are the cancer types where BIRC6-AS2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Median	All	0.542	0.699	<.001	110	view →
ACC	DFS	Median	All	0.340	0.763	<.001	54	view →
KICH	OS	Median	II,III,IV	0.751	1.000	.005	52	view →
BLCA	DFS	Median	IV	0.312	0.167	.003	32	view →
CHOL	OS	Median	III,IV	0.286	1.000	.008	15	view →
COAD	DFS	Median	IV	0.609	0.363	.012	15	view →
KIRP	DFS	Tertile	All	0.565	0.825	.007	14	view →
THYM	DFS	Quartile	II,III,IV	1.000	0.553	.016	12	view →
UCS	DFS	Median	IV	0.952	0.473	.018	12	view →
SKCM	OS	Quartile	III,IV	0.715	0.329	.002	10	view →
UVM	DFS	Quartile	III,IV	0.230	0.674	.017	8	view →
PCPG	OS	Median	All	0.728	1.000	.014	7	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

BIRC6-AS2–KIRC (DFS)

Open the KIRC breakdown →