BIRC3

Across TCGA patient cohorts, BIRC3 RNA expression is significantly associated with the protein abundance of many other proteins, with 21,355 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible BIRC3-associated proteins across cancer lineages are PTPRC, FMNL1, and GBP2. Each is linked with BIRC3 in more than 9 cancer types. Because this analysis shows association rather than direction, both BIRC3-to-partner and partner-to-BIRC3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, BIRC3 versus PTPRC in OV, with a Pearson correlation of 0.49.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (BIRC3→partner) and Y-score (partner→BIRC3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	PTPRC →	+0.741	+1.617	.001	<.001	3	10
LSCC	FMNL1 →	+0.605	+1.161	<.001	<.001	3	10
UCEC	GBP2 →	+0.738	+1.446	<.001	<.001	3	10
UCEC	ITGAL →	+0.630	+1.161	<.001	<.001	3	10
OV	PSMB10 →	+0.622	+2.140	<.001	<.001	3	9
GBM	PTPN6 →	+0.579	+1.026	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 21,355 associations by consensus.

BIRC3 vs PTPRC — OV

Explore this scatter interactively →