BIN2P2

Across TCGA patient cohorts, BIN2P2 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,236 significant associations in total. STAD shows the largest number of these associations.

The most reproducible BIN2P2-associated GO terms across cancer lineages are Regulation of leukocyte mediated immunity, Neutrophil migration, and Phagocytosis. Each is linked with BIN2P2 in more than 17 cancer types. Because this analysis shows association rather than direction, both BIN2P2-to-partner and partner-to-BIN2P2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of leukocyte mediated immunity grouped by BIN2P2-low versus BIN2P2-high in KIRP.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (BIN2P2→partner) and Y-score (partner→BIN2P2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIRP	Regulation of leukocyte mediated immunity →	+0.035	+0.008	<.001	<.001	3	18
LAML	Neutrophil migration →	+0.045	+0.134	<.001	.003	3	16
STAD	Phagocytosis →	+0.050	+0.055	<.001	<.001	3	16
KIRP	Myeloid leukocyte activation →	+0.044	+0.013	<.001	<.001	3	16
KIRP	Positive regulation of alpha-beta T cell activation →	+0.048	+0.010	<.001	<.001	3	16
ESCA	Lymphocyte activation involved in immune response →	+0.047	+0.016	<.001	.008	1	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,236 associations by consensus.

Regulation of leukocyte mediated immunity by BIN2P2 expression — KIRP

Explore this box plot interactively →