BIN2P2

Across TCGA pan-cancer cohorts, BIN2P2 RNA is linked to patient survival in 15 of 34 cancer types, making it the most broadly survival-associated BIN2P2 data layer.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where higher BIN2P2 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated BIN2P2 expression acts as an unfavorable survival marker, although some lineages such as BLCA and CESC show a favorable association.

LUSC, ACC, and MESO are the cancer types where BIN2P2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUSC	OS	Tertile	III,IV	0.229	0.595	.001	72	view →
ACC	OS	Tertile	All	0.186	0.751	<.001	69	view →
MESO	DFS	Tertile	III,IV	0.176	0.430	.007	36	view →
THCA	DFS	Tertile	II,III,IV	0.692	0.944	<.001	36	view →
STAD	DFS	Quartile	II,III,IV	0.342	0.564	.004	35	view →
UVM	DFS	Tertile	All	0.221	0.618	.042	27	view →
BLCA	OS	Tertile	IV	1.000	0.260	.035	21	view →
CESC	OS	Tertile	All	0.950	0.560	.021	18	view →
LIHC	OS	Tertile	II,III,IV	0.394	0.701	.001	18	view →
LAML	DFS	Quartile	All	0.439	0.724	.022	12	view →
GBM	OS	Tertile	All	0.280	0.464	.001	9	view →
LGG	DFS	Tertile	All	0.704	0.840	.023	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 15 lineages.

BIN2P2–LUSC (OS)

Open the LUSC breakdown →