BIK

Across TCGA patient cohorts, BIK protein abundance is significantly associated with the RNA expression of many other genes, with 347 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible BIK-associated genes across cancer lineages are USP9Y, RBM18, and TAS2R10. Each is linked with BIK in more than 1 cancer types. Because this analysis shows association rather than direction, both BIK-to-partner and partner-to-BIK results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, BIK versus USP9Y in CCRCC, with a Pearson correlation of 0.35.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BIK→partner) and Y-score (partner→BIK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	USP9Y →	+2.326	+0.289	.002	.001	3	1
CCRCC	RBM18 →	+0.226	+0.308	.005	.001	3	1
CCRCC	TAS2R10 →	+0.469	+0.284	.001	.004	3	1
CCRCC	SPATA1 →	+0.258	+0.298	.003	.002	3	1
CCRCC	KDM5D →	+1.641	+0.294	.006	.005	3	1
CCRCC	TXLNGY →	+1.669	+0.351	.002	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 347 associations by consensus.

BIK vs USP9Y — CCRCC

Explore this scatter interactively →