BIK

Across TCGA cell cohorts, BIK RNA expression is significantly associated with the go_rna of many other GO terms, with 4,467 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible BIK-associated GO terms across cancer lineages are Regulation of respiratory gaseous exchange by nervous system process, Regulation of white fat cell proliferation, and Maintenance of blood-brain barrier. Each is linked with BIK in more than 10 cancer types. Because this analysis shows association rather than direction, both BIK-to-partner and partner-to-BIK results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of respiratory gaseous exchange by nervous system process grouped by BIK-low versus BIK-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (BIK→partner) and Y-score (partner→BIK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Regulation of respiratory gaseous exchange by nervous system process →	-1.067	-2.046	<.001	<.001	3	11
LUNG_NSCLC_LUSC	Regulation of white fat cell proliferation →	-0.290	-2.287	.001	.002	3	11
LUNG_NSCLC_LUSC	Maintenance of blood-brain barrier →	+0.262	+2.778	.004	.001	3	10
OESOPHAGUS	Cell-cell adhesion mediated by cadherin →	+0.239	+1.555	<.001	.004	3	10
LUNG_SCLC	Calcium-independent cell-cell adhesion →	+0.641	+2.536	.005	<.001	3	10
LUNG_SCLC	Negative regulation of Arp2/3 complex-mediated actin nucleation →	+0.206	+2.061	.001	.003	2	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,467 associations by consensus.

Regulation of respiratory gaseous exchange by nervous system process by BIK expression — URINARY_TRACT

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