BICRA-AS1

Across TCGA pan-cancer cohorts, BICRA-AS1 RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated BICRA-AS1 data layer.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher BICRA-AS1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated BICRA-AS1 expression acts as an unfavorable survival marker, although some lineages such as BRCA and HNSC show a favorable association.

ACC, KIRC, and BRCA are the cancer types where BICRA-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	OS	Tertile	All	0.410	0.879	<.001	81	view →
KIRC	OS	Tertile	All	0.748	0.839	.001	70	view →
BRCA	DFS	Median	III,IV	0.872	0.715	<.001	69	view →
THYM	DFS	Quartile	All	0.712	0.915	<.001	62	view →
HNSC	DFS	Quartile	All	0.774	0.661	.007	32	view →
READ	DFS	Tertile	All	0.224	0.619	.002	26	view →
DLBC	DFS	Median	III,IV	0.140	0.917	.010	25	view →
UVM	DFS	Tertile	All	0.280	0.610	.032	18	view →
LUAD	OS	Quartile	All	0.769	0.644	.014	14	view →
TGCT	DFS	Median	All	0.712	0.868	.014	12	view →
LGG	DFS	Median	All	0.313	0.540	.003	10	view →
THCA	DFS	Tertile	III,IV	0.833	0.913	.034	10	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

BICRA-AS1–ACC (OS)

Open the ACC breakdown →