BICDL2

Across TCGA patient cohorts, BICDL2 mutation is significantly associated with the RNA expression of many other genes, with 293 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible BICDL2-associated genes across cancer lineages are RN7SKP171, RNA5SP423, and RNU7-67P. Each is linked with BICDL2 in more than 1 cancer types. Because this analysis shows association rather than direction, both BICDL2-to-partner and partner-to-BICDL2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SKP171 grouped by BICDL2-low versus BICDL2-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BICDL2→partner) and Y-score (partner→BICDL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	RN7SKP171 →	+0.092	+5.852	<.001	<.001	3	2
UCEC	RNA5SP423 →	+0.857	+2.454	<.001	.008	3	2
BLCA	RNU7-67P →	+0.894	+4.562	<.001	.006	3	2
CESC	LINC01849 →	+0.068	+3.345	<.001	.008	3	2
COAD	VN1R90P →	+0.159	+3.408	<.001	.009	3	2
CESC	NF1P10 →	+0.097	+4.247	<.001	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 293 associations by consensus.

RN7SKP171 by BICDL2 expression — CESC

Explore this box plot interactively →