Across TCGA patient cohorts, BICD2 mutation is significantly associated with the RNA expression of many other genes, with 4,081 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible BICD2-associated genes across cancer lineages are MRPL18, AURKB, and RCC1. Each is linked with BICD2 in more than 3 cancer types. Because this analysis shows association rather than direction, both BICD2-to-partner and partner-to-BICD2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BICD2→partner) and Y-score (partner→BICD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MRPL18 →	+0.314	+1.726	<.001	.001	3	4
UCEC	AURKB →	+0.424	+1.673	.007	.006	3	3
COAD	RCC1 →	+0.536	+3.210	.002	.009	3	3
UCEC	UQCR10 →	+0.293	+1.439	<.001	<.001	3	3
COAD	CIB1 →	+0.535	+3.200	.003	.009	3	3
UCEC	CHP1 →	+0.398	+1.740	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,081 associations by consensus.

Exploration

BICD2 survival (RNA) · tumor vs normal (RNA) · all BICD2 data types