BICD1

Across TCGA patient cohorts, BICD1 protein abundance is significantly associated with the RNA expression of many other genes, with 9,245 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible BICD1-associated genes across cancer lineages are PPFIBP1, LGALS1, and NES. Each is linked with BICD1 in more than 5 cancer types. Because this analysis shows association rather than direction, both BICD1-to-partner and partner-to-BICD1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, BICD1 versus PPFIBP1 in HNSC, with a Pearson correlation of 0.29.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BICD1→partner) and Y-score (partner→BICD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	PPFIBP1 →	+0.618	+0.338	.001	.002	3	6
LSCC	LGALS1 →	+1.261	+0.438	<.001	<.001	3	5
BRCA	NES →	+1.150	+0.437	<.001	<.001	3	5
UCEC	FKBP10 →	+0.969	+0.273	<.001	<.001	3	5
GBM	PDLIM7 →	+0.775	+0.332	<.001	<.001	3	5
GBM	LZTS1 →	+1.166	+0.401	<.001	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,245 associations by consensus.

BICD1 vs PPFIBP1 — HNSC

Explore this scatter interactively →