BHLHE41

Across TCGA patient cohorts, BHLHE41 protein abundance is significantly associated with the RNA expression of many other genes, with 9,147 significant associations in total. GBM shows the largest number of these associations.

The most reproducible BHLHE41-associated genes across cancer lineages are HMGCS1, ZBED3, and SYNCRIP. Each is linked with BHLHE41 in more than 2 cancer types. Because this analysis shows association rather than direction, both BHLHE41-to-partner and partner-to-BHLHE41 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, BHLHE41 versus HMGCS1 in GBM, with a Pearson correlation of -0.43.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BHLHE41→partner) and Y-score (partner→BHLHE41) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	HMGCS1 →	-0.895	-0.517	<.001	.001	3	2
OV	ZBED3 →	-1.035	-0.471	<.001	.002	3	2
GBM	SYNCRIP →	-0.684	-0.632	<.001	<.001	3	2
GBM	CCDC15 →	-0.825	-0.646	<.001	<.001	3	2
OV	CEP295 →	-0.944	-0.508	<.001	<.001	3	2
GBM	ZNF91 →	-0.736	-0.541	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,147 associations by consensus.

BHLHE41 vs HMGCS1 — GBM

Explore this scatter interactively →