BHLHE41

Across TCGA cell cohorts, BHLHE41 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,505 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible BHLHE41-associated GO terms across cancer lineages are Positive regulation of proteolysis, Cytolysis in another organism, and Actin filament capping. Each is linked with BHLHE41 in more than 9 cancer types. Because this analysis shows association rather than direction, both BHLHE41-to-partner and partner-to-BHLHE41 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of proteolysis grouped by BHLHE41-low versus BHLHE41-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (BHLHE41→partner) and Y-score (partner→BHLHE41) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Positive regulation of proteolysis →	+0.103	+1.769	<.001	<.001	3	10
LUNG_NSCLC_LUSC	Cytolysis in another organism →	+1.639	+1.915	.001	<.001	3	10
LIVER	Actin filament capping →	+0.176	+3.252	.001	<.001	3	10
BONE	Positive regulation of blood pressure by epinephrine-norepinephrine →	+0.458	+1.824	<.001	<.001	3	10
LUNG_NSCLC_LUSC	Regulation of Rho protein signal transduction →	+0.090	+1.784	.004	.003	3	10
LIVER	Barbed-end actin filament capping →	+0.221	+3.083	.004	.003	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,505 associations by consensus.

Positive regulation of proteolysis by BHLHE41 expression — SOFT_TISSUE

Explore this box plot interactively →