BHLHE40

Across TCGA patient cohorts, BHLHE40 protein abundance is significantly associated with the RNA expression of many other genes, with 8,359 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible BHLHE40-associated genes across cancer lineages are MIRLET7BHG, NCAM2, and NDRG1. Each is linked with BHLHE40 in more than 2 cancer types. Because this analysis shows association rather than direction, both BHLHE40-to-partner and partner-to-BHLHE40 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, BHLHE40 versus MIRLET7BHG in BRCA, with a Pearson correlation of 0.41.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BHLHE40→partner) and Y-score (partner→BHLHE40) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	MIRLET7BHG →	+1.045	+0.407	<.001	<.001	3	3
BRCA	NCAM2 →	+0.919	+0.325	.003	.001	3	3
UCEC	NDRG1 →	+1.748	+0.568	<.001	<.001	3	2
UCEC	ENO2 →	+1.415	+0.491	.001	.001	3	2
UCEC	VEGFA →	+1.353	+0.565	<.001	<.001	3	2
UCEC	PFKFB4 →	+1.161	+0.534	.003	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,359 associations by consensus.

BHLHE40 vs MIRLET7BHG — BRCA

Explore this scatter interactively →