BHLHE40

Across TCGA cell cohorts, BHLHE40 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible BHLHE40-associated genes across cancer lineages are OR56A1, OR52B2, and OR10W1. Each is linked with BHLHE40 in more than 1 cancer types. Because this analysis shows association rather than direction, both BHLHE40-to-partner and partner-to-BHLHE40 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR56A1 grouped by BHLHE40-low versus BHLHE40-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BHLHE40→partner) and Y-score (partner→BHLHE40) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	OR56A1 →	+0.028	+4.523	.004	.004	3	1
BLOOD_Lymphoma	OR52B2 →	+0.026	+4.714	<.001	.002	3	1
LARGE_INTESTINE	OR10W1 →	+0.019	+4.977	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

OR56A1 by BHLHE40 expression — BLOOD_Lymphoma

Explore this box plot interactively →