BGLT3

Across TCGA pan-cancer cohorts, BGLT3 RNA is linked to patient survival in 3 of 34 cancer types, making it the most broadly survival-associated BGLT3 data layer compared with 1 for mutation status.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher BGLT3 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated BGLT3 expression acts as an unfavorable survival marker, although some lineages such as STAD show a favorable association.

ACC, SARC, and STAD are the cancer types where BGLT3 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	OS	Tertile	All	0.145	0.888	<.001	99	view →
SARC	DFS	Tertile	All	0.129	0.595	.005	18	view →
STAD	OS	Tertile	IV	0.682	0.258	.040	9	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

BGLT3–ACC (OS)

Open the ACC breakdown →