BEX1

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, BEX1 mutation is significantly associated with the RNA expression of many other genes, with 841 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible BEX1-associated genes across cancer lineages are MIR7702, RNU6-492P, and FCF1P9. Each is linked with BEX1 in more than 1 cancer types. Because this analysis shows association rather than direction, both BEX1-to-partner and partner-to-BEX1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR7702 grouped by BEX1-low versus BEX1-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BEX1→partner) and Y-score (partner→BEX1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
COADMIR7702 →+0.481+7.741<.001.00932
STADRNU6-492P →+0.642+4.691<.001.00332
STADFCF1P9 →+0.288+5.690<.001<.00132
LUSCSPANXN3 →+0.217+3.684<.001.00931
LUSCRNU6-212P →+0.339+3.781.002.00731
LUSCRNU6-207P →+0.281+3.815.007.00731
Each partner links to its Q-omics profile. Showing the 6 strongest of 841 associations by consensus.

MIR7702 by BEX1 expression — COAD

Box plot of MIR7702 in BEX1-low vs BEX1-high samples in COAD.

Explore this box plot interactively →

Exploration