BEST4

Across TCGA patient cohorts, BEST4 protein abundance is significantly associated with the RNA expression of many other genes, with 162 significant associations in total. COAD shows the largest number of these associations.

The most reproducible BEST4-associated genes across cancer lineages are RABGGTA, MED26, and UBTF. Each is linked with BEST4 in more than 1 cancer types. Because this analysis shows association rather than direction, both BEST4-to-partner and partner-to-BEST4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, BEST4 versus RABGGTA in COAD, with a Pearson correlation of 0.59.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BEST4→partner) and Y-score (partner→BEST4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	RABGGTA →	+0.748	+1.282	.007	.005	3	1
COAD	MED26 →	+0.518	+1.282	.001	.005	3	1
COAD	UBTF →	+0.669	+1.282	.006	.005	3	1
COAD	DRG2 →	+0.546	+1.282	.003	.005	3	1
COAD	MPP2 →	+0.697	+1.282	.002	.005	3	1
COAD	SH3D19 →	+0.732	+1.282	.003	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 162 associations by consensus.

BEST4 vs RABGGTA — COAD

Explore this scatter interactively →